Fumika Yakushiji : rechercher sur Z-Library

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1

3-Nitro-2-pyridinesulfenyl-mediated solid-phase disulfide ligation in the synthesis of disulfide bond-containing cyclic peptides

Taguchi, Akihiro, Fukumoto, Kentarou, Asahina, Yuya, Kajiyama, Akihiro, Shimura, Shunsuke, Hamada, Keisuke, Takayama, Kentaro, Yakushiji, Fumika, Hojo, Hironobu, Hayashi, Yoshio

Journal:

Organic & Biomolecular Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 835 KB

english, 2015

2

Design, synthesis, and biological evaluation of novel dipeptide-type SARS-CoV 3CL protease inhibitors: Structure–activity relationship study

Thanigaimalai, Pillaiyar, Konno, Sho, Yamamoto, Takehito, Koiwai, Yuji, Taguchi, Akihiro, Takayama, Kentaro, Yakushiji, Fumika, Akaji, Kenichi, Kiso, Yoshiaki, Kawasaki, Yuko, Chen, Shen-En, Naser-Tav

Journal:

European Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2013

3

Identification of the Minimum Peptide from Mouse Myostatin Prodomain for Human Myostatin Inhibition

Takayama, Kentaro, Noguchi, Yuri, Aoki, Shin, Takayama, Shota, Yoshida, Momoko, Asari, Tomo, Yakushiji, Fumika, Nishimatsu, Shin-ichiro, Ohsawa, Yutaka, Itoh, Fumiko, Negishi, Yoichi, Sunada, Yoshihid

Journal:

Journal of Medicinal Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 743 KB

english, 2015

4

Total synthesis of plusbacin A3 and its dideoxy derivative using a solvent-dependent diastereodivergent Joullié–Ugi three-component reaction

Katsuyama, Akira, Yakushiji, Fumika, Ichikawa, Satoshi

Journal:

Journal of Organic Chemistry

Année:

2018

Langue:

english

Fichier:

PDF, 899 KB

english, 2018

5

Water-Soluble Prodrug of Antimicrotubule Agent Plinabulin: Effective Strategy with Click Chemistry

Dr. Fumika Yakushiji, Hironari Tanaka, Kyohei Muguruma, Takahiro Iwahashi, Yuri Yamazaki, Prof. Dr. Yoshio Hayashi

Journal:

Chemistry - A European Journal

Année:

2011

Langue:

english

Fichier:

PDF, 362 KB

english, 2011

6

Tubulin photoaffinity labeling study with a plinabulin chemical probe possessing a biotin tag at the oxazole

Yuri Yamazaki, Yui Kido, Koushi Hidaka, Hiroyuki Yasui, Yoshiaki Kiso, Fumika Yakushiji, Yoshio Hayashi

Journal:

Bioorganic & Medicinal Chemistry

Année:

2011

Langue:

english

Fichier:

PDF, 884 KB

english, 2011

7

Total synthesis of (+)-negamycin and its 5-epi-derivative

Shigenobu Nishiguchi, Magne O. Sydnes, Akihiro Taguchi, Thomas Regnier, Tetsuya Kajimoto, Manabu Node, Yuri Yamazaki, Fumika Yakushiji, Yoshiaki Kiso, Yoshio Hayashi

Journal:

Année:

2010

Langue:

english

Fichier:

PDF, 400 KB

english, 2010

8

Diastereoselective construction of substituted tetrahydropyrans using an intramolecular oxy-Michael strategy

Fumika Yakushiji, Jacques Maddaluno, Masahiro Yoshida, Kozo Shishido

Journal:

Tetrahedron Letters

Année:

2009

Langue:

english

Fichier:

PDF, 301 KB

english, 2009

9

Anti-microtubule ‘plinabulin’ chemical probe KPU-244-B3 labeled both α- and β-tubulin

Yuri Yamazaki, Makiko Sumikura, Koushi Hidaka, Hiroyuki Yasui, Yoshiaki Kiso, Fumika Yakushiji, Yoshio Hayashi

Journal:

Bioorganic & Medicinal Chemistry

Année:

2010

Langue:

english

Fichier:

PDF, 826 KB

english, 2010

10

Development of a solid-supported biotinylation reagent for efficient biotin labeling of SH groups on small molecules

Kentarou Fukumoto, Kumi Adachi, Akihiro Kajiyama, Yuri Yamazaki, Fumika Yakushiji, Yoshio Hayashi

Journal:

Tetrahedron Letters

Année:

2012

Langue:

english

Fichier:

PDF, 461 KB

english, 2012

11

Synthesis and structure–activity relationships of benzophenone-bearing diketopiperazine-type anti-microtubule agents

Yuri Yamazaki, Makiko Sumikura, Yurika Masuda, Yoshiki Hayashi, Hiroyuki Yasui, Yoshiaki Kiso, Takumi Chinen, Takeo Usui, Fumika Yakushiji, Barbara Potts, Saskia Neuteboom, Michael Palladino, George K

Journal:

Bioorganic & Medicinal Chemistry

Année:

2012

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2012

12

Novel Hybrid-Type Antimicrobial Agents Targeting the Switch Region of Bacterial RNA Polymerase

Yakushiji, Fumika, Miyamoto, Yuko, Kunoh, Yuki, Okamoto, Reiko, Nakaminami, Hidemasa, Yamazaki, Yuri, Noguchi, Norihisa, Hayashi, Yoshio

Journal:

ACS Medicinal Chemistry Letters

Année:

2013

Langue:

english

Fichier:

PDF, 1.93 MB

english, 2013

13

Development of potent dipeptide-type SARS-CoV 3CL protease inhibitors with novel P3 scaffolds: Design, synthesis, biological evaluation, and docking studies

Thanigaimalai, Pillaiyar, Konno, Sho, Yamamoto, Takehito, Koiwai, Yuji, Taguchi, Akihiro, Takayama, Kentaro, Yakushiji, Fumika, Akaji, Kenichi, Chen, Shen-En, Naser-Tavakolian, Aurash, Schön, Arne, Fr

Journal:

European Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 2.27 MB

english, 2013

14

Design and synthesis of new tripeptide-type SARS-CoV 3CL protease inhibitors containing an electrophilic arylketone moiety

Konno, Sho, Thanigaimalai, Pillaiyar, Yamamoto, Takehito, Nakada, Kiyohiko, Kakiuchi, Rie, Takayama, Kentaro, Yamazaki, Yuri, Yakushiji, Fumika, Akaji, Kenichi, Kiso, Yoshiaki, Kawasaki, Yuko, Chen, S

Journal:

Bioorganic & Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 4.83 MB

english, 2013

15

Total Synthesis of (+)-Lasonolide A

Yoshimura, Tomoyuki, Yakushiji, Fumika, Kondo, Shingo, Wu, Xiaofeng, Shindo, Mitsuru, Shishido, Kozo

Journal:

Organic Letters

Année:

2006

Langue:

english

Fichier:

PDF, 105 KB

english, 2006

16

Palladium-catalyzed C3-selective mono-arylation of 4-hydroxycoumarin

Yakushiji, Fumika, Haramo, Masako, Miyadera, Yukari, Uchiyama, Chihiro, Takayama, Kentaro, Hayashi, Yoshio

Journal:

Tetrahedron Letters

Année:

2014

Langue:

english

Fichier:

PDF, 1.03 MB

english, 2014

17

Development of a New Benzophenone–Diketopiperazine-Type Potent Antimicrotubule Agent Possessing a 2-Pyridine Structure

Hayashi, Yoshiki, Takeno, Haruka, Chinen, Takumi, Muguruma, Kyohei, Okuyama, Kohei, Taguchi, Akihiro, Takayama, Kentaro, Yakushiji, Fumika, Miura, Masahiko, Usui, Takeo, Hayashi, Yoshio

Journal:

ACS Medicinal Chemistry Letters

Année:

2014

Langue:

english

Fichier:

PDF, 1.02 MB

english, 2014

18

Negamycin Analogue with Readthrough-Promoting Activity as a Potential Drug Candidate for Duchenne Muscular Dystrophy

Taguchi, Akihiro, Nishiguchi, Shigenobu, Shiozuka, Masataka, Nomoto, Takao, Ina, Mayuko, Nojima, Shouta, Matsuda, Ryoichi, Nonomura, Yoshiaki, Kiso, Yoshiaki, Yamazaki, Yuri, Yakushiji, Fumika, Hayash

Journal:

ACS Medicinal Chemistry Letters

Année:

2012

Langue:

english

Fichier:

PDF, 1.19 MB

english, 2012

19

Discovery of Selective Hexapeptide Agonists to Human Neuromedin U Receptors Types 1 and 2

Takayama, Kentaro, Mori, Kenji, Taketa, Koji, Taguchi, Akihiro, Yakushiji, Fumika, Minamino, Naoto, Miyazato, Mikiya, Kangawa, Kenji, Hayashi, Yoshio

Journal:

Journal of Medicinal Chemistry

Année:

2014

Langue:

english

Fichier:

PDF, 1.82 MB

english, 2014

20

Discovery of Natural Products Possessing Selective Eukaryotic Readthrough Activity: 3- epi -Deoxynegamycin and Its Leucine Adduct

Taguchi, Akihiro, Hamada, Keisuke, Kotake, Masaya, Shiozuka, Masataka, Nakaminami, Hidemasa, Pillaiyar, Thanigaimalai, Takayama, Kentaro, Yakushiji, Fumika, Noguchi, Norihisa, Usui, Takeo, Matsuda, Ry

Journal:

Année:

2014

Langue:

english

Fichier:

PDF, 317 KB

english, 2014

21

Discovery of Potent Hexapeptide Agonists to Human Neuromedin U Receptor 1 and Identification of Their Serum Metabolites

Takayama, Kentaro, Mori, Kenji, Sohma, Yuko, Taketa, Koji, Taguchi, Akihiro, Yakushiji, Fumika, Minamino, Naoto, Miyazato, Mikiya, Kangawa, Kenji, Hayashi, Yoshio

Journal:

ACS Medicinal Chemistry Letters

Année:

2015

Langue:

english

Fichier:

PDF, 1.37 MB

english, 2015

22

Structure–Activity Relationship Studies of 3- epi -Deoxynegamycin Derivatives as Potent Readthrough Drug Candidates

Hamada, Keisuke, Taguchi, Akihiro, Kotake, Masaya, Aita, Suguru, Murakami, Saori, Takayama, Kentaro, Yakushiji, Fumika, Hayashi, Yoshio

Journal:

ACS Medicinal Chemistry Letters

Année:

2015

Langue:

english

Fichier:

PDF, 554 KB

english, 2015

23

Enantioselective Constructionof the C 1 -C 16 Segment of Lasonolide A

Deba, Tatsuya, Yakushiji, Fumika, Shindo, Mitsuru, Shishido, Kozo

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 51 KB

english, 2003

24

Novel hybrid compound of a plinabulin prodrug with an IgG binding peptide for generating a tumor selective non-covalent-type antibody-drug conjugate

Muguruma, Kyohei, Yakushiji, Fumika, Kawamata, Ryosuke, Akiyama, Daichi, Arima, Risako, Shirasaka, Takuya, Kikkawa, Yamato, Taguchi, Akihiro, Takayama, Kentaro, Fukuhara, Takeshi, Watabe, Tetsuro, Ito

Journal:

Bioconjugate Chemistry

Année:

2016

Langue:

english

Fichier:

PDF, 942 KB

english, 2016

25

ChemInform Abstract: Medicinal Chemistry and Chemical Biology of Diketopiperazine-Type Antimicrotubule and Vascular-Disrupting Agents

Hayashi, Yoshio, Yamazaki-Nakamura, Yuri, Yakushiji, Fumika

Journal:

Année:

2014

Fichier:

PDF, 18 KB

2014

26

Identification of a Degrading Enzyme in Human Serum that Hydrolyzes a C-terminal Core Sequence of Neuromedin U

Takayama, Kentaro, Taguchi, Akihiro, Yakushiji, Fumika, Hayashi, Yoshio

Journal:

Année:

2015

Langue:

english

Fichier:

PDF, 1.34 MB

english, 2015

27

Effect of N-Terminal Acylation on the Activity of Myostatin Inhibitory Peptides

Takayama, Kentaro, Nakamura, Akari, Rentier, Cédric, Mino, Yusaku, Asari, Tomo, Saga, Yusuke, Taguchi, Akihiro, Yakushiji, Fumika, Hayashi, Yoshio

Journal:

Année:

2016

Langue:

english

Fichier:

PDF, 673 KB

english, 2016

28

Development of the Thiol-Selective Solid-Supported Oligoarginine-Conjugating Reagent KSH-2

Fukumoto, Kentarou, Kajiyama, Akihiro, Shimura, Shunsuke, Taketa, Koji, Kimura, Shinichiro, Taguchi, Akihiro, Takayama, Kentaro, Yakushiji, Fumika, Hayashi, Yoshio

Journal:

Asian Journal of Organic Chemistry

Année:

2015

Langue:

english

Fichier:

PDF, 636 KB

english, 2015

29

ChemInform Abstract: Palladium-Catalyzed C3-Selective Mono-Arylation of 4-Hydroxycoumarin.

Yakushiji, Fumika, Haramo, Masako, Miyadera, Yukari, Uchiyama, Chihiro, Takayama, Kentaro, Hayashi, Yoshio

Journal:

Année:

2014

Fichier:

PDF, 19 KB

2014

30

Prodrug Study of Plinabulin Using a Click Strategy Focused on the Effects of a Replaceable Water-Solubilizing Moiety

Yakushiji, Fumika, Tanaka, Hironari, Muguruma, Kyohei, Iwahashi, Takahiro, Yamazaki, Yuri, Hayashi, Yoshio

Année:

2012

Langue:

english

Fichier:

PDF, 581 KB

english, 2012

31

Medicinal Chemistry and Chemical Biology of Diketopiperazine-Type Antimicrotubule and Vascular-Disrupting Agents

Hayashi, Yoshio, Yamazaki-Nakamura, Yuri, Yakushiji, Fumika

Journal:

CHEMICAL & PHARMACEUTICAL BULLETIN

Année:

2013

Langue:

english

Fichier:

PDF, 5.39 MB

english, 2013

32

HIV-1 susceptibility of transgenic rat-derived primary macrophage/T cells and a T cell line that express human receptors, CyclinT1 and CRM1 genes

Shida, Hisatoshi, Okada, Hiroyuki, Suzuki, Hajime, Zhang, Xianfeng, Chen, Jing, Tsunetsugu-Yokota, Yasuko, Tanaka, Yuetsu, Yakushiji, Fumika, Hayashi, Yoshio

Journal:

Année:

2017

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2017

33

One-pot Selective Synthesis of 2,3-Dihydro-4 H -Furo[3,2- c ]coumarins by Palladium-Catalyzed Silver-Assisted Propargylation/Intramolecular 5- exo- dig Cyclization

Uchiyama, Chihiro, Miyadera, Yukari, Hayashi, Yoshio, Yakushiji, Fumika

Journal:

ChemistrySelect

Année:

2017

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2017

34

Click strategy using disodium salts of amino acids improves the water solubility of plinabulin and KPU-300

Yakushiji, Fumika, Muguruma, Kyohei, Hayashi, Yoshiki, Shirasaka, Takuya, Kawamata, Ryosuke, Tanaka, Hironari, Yoshiwaka, Yushi, Taguchi, Akihiro, Takayama, Kentaro, Hayashi, Yoshio

Journal:

Bioorganic & Medicinal Chemistry

Année:

2017

Langue:

english

Fichier:

PDF, 796 KB

english, 2017

35

Impact of Structures of Macrocyclic Michael Acceptors on Covalent Proteasome Inhibition

Kitahata, Shun, Yakushiji, Fumika, Ichikawa, Satoshi

Journal:

Chemical Science

Année:

2017

Langue:

english

Fichier:

PDF, 3.96 MB

english, 2017

36

Total Synthesis of Tunicamycin V

Yamamoto, Kazuki, Yakushiji, Fumika, Matsumaru, Takanori, Ichikawa, Satoshi

Journal:

Organic Letters

Année:

2017

Langue:

english

Fichier:

PDF, 1.65 MB

english, 2017

37

Study of the structure-activity relationship of polymyxin analogues

Kinoshita, Yuhei, Yakushiji, Fumika, Matsui, Hidehito, Hanaki, Hideaki, Ichikawa, Satoshi

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2018

Langue:

english

Fichier:

PDF, 681 KB

english, 2018

38

Solid-Phase Modular Synthesis of Park Nucleotide and Lipids I and II Analogues

Katsuyama, Akira, Sato, Kousuke, Yakushiji, Fumika, Matsumaru, Takanori, Ichikawa, Satoshi

Année:

2018

Langue:

english

Fichier:

PDF, 1.28 MB

english, 2018

39

New Chemistry with Old Functional Groups: New Insight of Amide Bond Formation

Yakushiji, Fumika

Journal:

Journal of Synthetic Organic Chemistry Japan

Année:

2011

Fichier:

PDF, 664 KB

2011

40

Synthesis and biological evaluation of a MraY selective analogue of tunicamycins

Yamamoto, Kazuki, Sato, Toyotaka, Hikiji, Yuta, Katsuyama, Akira, Matsumaru, Takanori, Yakushiji, Fumika, Yokota, Shin-Ichi, Ichikawa, Satoshi

Journal:

Nucleosides Nucleotides & Nucleic Acids

Année:

2019

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2019

41

Synthesis and biological evaluation of a MraY selective analogue of tunicamycins

Yamamoto, Kazuki, Sato, Toyotaka, Hikiji, Yuta, Katsuyama, Akira, Matsumaru, Takanori, Yakushiji, Fumika, Yokota, Shin-Ichi, Ichikawa, Satoshi

Journal:

Nucleosides Nucleotides & Nucleic Acids

Année:

2019

Fichier:

PDF, 1.67 MB

2019

42

Development of cyclic peptide derivatives from the N-terminal region of LANA for targeting the nucleosome acidic patch

Yakushiji, Fumika, Ishikawa, Aoi, Katsuyama, Akira, Ichikawa, Satoshi

Journal:

Bioorganic & Medicinal Chemistry Letters

Année:

2019

Fichier:

PDF, 653 KB

2019

43

Diversity-oriented Symposium: Diversity Experiences through Study Abroad; Diversity-orientedシンポジウム：若手海外挑戦がひらく多様性のトビラ;

Yakushiji, Fumika, Nakayama, Atsushi

Journal:

YAKUGAKU ZASSHI

Année:

2020

Fichier:

PDF, 166 KB

2020

44

Total Synthesis of Echinomycin and Its Analogues

Kojima, Keita, Yakushiji, Fumika, Katsuyama, Akira, Ichikawa, Satoshi

Journal:

Organic Letters

Année:

2020

Fichier:

PDF, 1005 KB

2020

45

Total Synthesis of Acaulide and Acaulone A

Hirabayashi, Jun, Yakushiji, Fumika, Katsuyama, Akira, Ichikawa, Satoshi

Journal:

Organic Letters

Année:

2020

Fichier:

PDF, 1003 KB

2020

46

Elucidating the Structural Requirement of Uridylpeptide Antibiotics for Antibacterial Activity

Terasawa, Yuma, Sataka, Chisato, Sato, Toyotaka, Yamamoto, Kazuki, Fukushima, Yukari, Nakajima, Chie, Suzuki, Yasuhiko, Katsuyama, Akira, Matsumaru, Takanori, Yakushiji, Fumika, Yokota, Shin-ichi, Ich

Journal:

Journal of Medicinal Chemistry

Année:

2020

Fichier:

PDF, 1.58 MB

2020